![]() 98ĬB-CAPs may be helpful in the diagnosis of SLE. 98-101 A prospective study of active SLE with elevated CB-CAPs at baseline found that a reduction of E-C4d, E-C3d, and the serum titer of C1q at follow-up was significantly associated with clinical improvement using validated measures of disease activity. 97 Cross-sectional and longitudinal studies have found that measurement of these cell-bound complement activation products (CB-CAPs) is useful in monitoring disease activity. Quismorio, in Dubois' Lupus Erythematosus and Related Syndromes (Ninth Edition), 2019 Cell-Bound Complement Activation ProductsĬ4d and C3d bind covalently to erythrocytes (E-C4d, E-C3d), to B lymphocytes (B-C4d), and to reticulocytes (R-C4d) to form a stable long-lived cell-bound marker that can be quantified by flow cytometry.
0 Comments
Leave a Reply. |
AuthorWrite something about yourself. No need to be fancy, just an overview. ArchivesCategories |